SULM – Schweizerische Union für Labormedizin | Union Suisse de Médecine de Laboratoire | Swiss Union of Laboratory Medicine

Sie sind hier | Vous êtes ici:

E FISIC1 , B SIMCIC2 , Š DVORNIK1 , S HRABRIC1

1Department of Laboratory Diagnosis,Clinical Hospital Centre, Rijeka, Croatia, 2Department of Internal Medicine, Rijeka University School of Medicine and Clinical Hospital Centre, Rijeka, Croatia

ANTICARDIOLIPIN ANTIBODIES IN PATIENTS WITH INFLAMMATORY BOWEL DISEASE

 

INTRODUCTION: Anticardiolipin antibodies (aCL) are circulating serum antibodies often associated with reccurent arterial and venous thromboembolism. They are detected in autoimune disease as well as in inflammatory bowel disease (IBD). The aim of the study is to compare the values of aCL, fibrinogen and platelets in patients with IBD and healthy controls.
MATERIALS AND METHODS: Sera were collected in 30 hospitally treated patients with IBD (14 with Chrons disease and 16 of the patients had moderate-severe ulcerative colitis). Sera from 10 healthy volunteers were control. IgG aCL was determined by ELISA test (Milenia, DPC, USA), fibrinogen by coagulometric measure (Behring fibrinometer A, Germany) and platelet count was measured by impendation technique (Technicon H-3, Bayer, Germany).
RESULTS: Patients with IBD had significant (p < 0,05) elevated aCL (15,9 U/L) compared with healthy controls (3,7 U/L). Values of fibrinogen in IBD patients were 5,2 g/L, and 2,3 g/L in controls (p < 0,05). There was no significant difference in platelets count. Only 1 patient has thromboembolic complications.
CONCLUSION: According to our results there was no connection between elevated aCL in patients with IBD and thromboembolic complications.

Agenda

07. & 08.03.2019: Swiss eHealth Forum - Digitales Gesundheitswesen – Hope and > mehr

pipette

pipette 06/2018: Die Analyse der Darmflora | Analyse du microbiote

Aktuelle Ausgabe als E-Paper lesen

Jobs

17.12.2018: Cheflaboranten/in 80%, (HFR) Tafers